HCID 20523293, compound → HCID 10013995, compound

Participants

Reaction Steps

34 g (93.8 mmol) of benzyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carbamate are hydrogenated at room temperature and normal pressure in 300 ml of methanol in the presence of 4 g of 10 percent palladium/carbon. After removal of the catalyst and evaporation, the residue is recrystallized from ethyl acetate and hexane. There is obtained 3-amino-4,5-dihydro-5-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-one of melting point 202°-204°.

Provenance & Evidence