Carbon Dioxide → HCID 54105642, compound

Participants

Reaction Steps

5.8 g (18.2 mmol) of (S)-7-chloro-11,12,13,13a-tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid are heated to 230°. After completion of the carbon dioxide evolution, the melt is treated with ethyl acetate. The solid material is filtered off under suction and dried. There is obtained (S)-7-chloro-11,12,13,13a-tetrahydro-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepin-9-one of melting point 216°-217°.

Provenance & Evidence