反应详情

A solution of 2-bromobenzoyl chloride (0.12 mole) in dioxane (50 ml) is added to a mixture of 1-hydrazino-4-chlorophthalazine (0.1 mole), triethylamine (0.12 mole) and dioxane (200 ml). The reaction mixture is refluxed for five hours then the solvent is evaporated off and the obtained residue is washed with a small amount of water and crystallized from methanol giving the compound of the title in 60% yield. M.p. 203°-04° C.

1. temperatureThe reaction mixture is refluxed for five hours
2. customthe solvent is evaporated off
3. washthe obtained residue is washed with a small amount of water
4. customcrystallized from methanol giving the compound of the title in 60% yield