Pyrrolidine → 1,2,4-Triazolo(3,4-a)phthalazine, 6-phenyl-3-(1-pyrrolidinyl)-

Participants

Reaction Conditions

Reaction Steps

A mixture of 3-chloro-6-phenyl-1,2,4-triazolo[3,4-a]phthalazine (4.5 g), pyrrolidine (6 ml) and ethanol (40 ml) is poured in a steel cylinder and heated to 100° C. for 8 hours. Then the mixture is cooled, and concentrated to dryness by evaporating off the solvent. The obtained residue is washed with water and crystallized from ethanol giving 3.5 g of the compound of the title. M.p. 245°-47° C.

Provenance & Evidence