Sodium Hydroxide → 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-2-mercapto-

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Reaction Steps

The product from Step A was added to 20% sodium hydroxide solution (250 mL) and heated to 70°-75° C. with stirring for one hour. The resulting solution was chilled in an ice bath and added rapidly, with stirring, to cold 10% hydrochloric acid (350 mL). The yellow solid was collected, washed with water and dried at 50° C.; yield 36 g.

Provenance & Evidence