HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetylene → HCID 14405340, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetylene | HCID 10821 | — |
| Reactant | HCID 21283714 | HCID 21283714 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Catalyst | HCID 178418476 | HCID 178418476 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 14405340 | HCID 14405340 | 71.4% |
Reaction Steps
In a manner similar to Step D of Example 1, the reaction of 1.3 gram (0.013 mole) of phenylacetylene, 50 ml of triethylamine, 3.2 grams (0.011 mole) of 5-iodo-2-(thien-2-yl)thiazole, 0.080 gram (1.1×10-4 mole) of dichlorobis(triphenylphosphine)palladium (II), and 0.022 gram (1.1×10-4 mole) of copper(I) iodide produced 2.1 grams of 1-phenyl-2-[2-(thien-2-yl)thiazol-5-yl]ethyne as a solid, m.p. 94°-96° C., Compound 22 of Table 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788207 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-ad8dc8c5acc44af69892a32e55ce8e67 |
| Source note | uspto-grants-1988_11 |