Chlorosuccinimide → HCID 21283210, compound

HRID 2232427Notes

Reaction equation

HRID 2232427 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5](/[C:7](=[N:11]/[O:12][CH2:13][C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])/[C:8]([OH:10])=[O:9])[N:6]=1.[Cl:21]N1C(=O)CCC1=O>CCCCCC>[NH2:1][C:2]1[S:3][C:4]([Cl:21])=[C:5](/[C:7](=[N:11]/[O:12][CH2:13][C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])/[C:8]([OH:10])=[O:9])[N:6]=1

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 10870340HCID 10870340, compound

Product 1

HCID 21283210HCID 21283210, compoundYield 97.2%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Six grams of 2-(2-aminothiazol-4-yl)-2(Z)-(tert-butoxycarbonylmethoxyimino)acetic acid and 3.2 g of N-chlorosuccinimide are reacted in the manner of Reference Example 35 and the product obtained is solidified by treating hexane to give 6.5 g of the above-identified compound as a powder.

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-fa64692bea1f4361b1cdfcbe344f2125
Source dataset
uspto-grants-1988_11
Patent number
US04788185

Reaction notes

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