HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-3-benzyloxypyridine → 8-(Benzyloxy)imidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-3-benzyloxypyridine | HCID 90334 | — |
| Reactant | Acetaldehyde, bromo- | HCID 105131 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 8-(Benzyloxy)imidazo[1,2-a]pyridine | HCID 13432974 | — |
Reaction Steps
2-Amino-3-benzyloxypyridine is reacted with bromoacetaldehye in aqueous tetrahydrofuran in the presence of sodium hydrogen carbonate, whereby the above-identified compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788185 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-3ea6532eee3f4137af696f061fdf8ff4 |
| Source note | uspto-grants-1988_11 |