Ethyl Bromide → HCID 21283796, compound

HRID 2232441Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:12]=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:19]([F:22])([F:21])[F:20])[NH:10][N:9]=1.[CH2:23](Br)[CH3:24]>>[CH2:23]([N:9]1[C:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[Cl:1])=[N:12][C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:19]([F:22])([F:20])[F:21])=[N:10]1)[CH3:24]

Participants

Reactant 2

HCID 6332Ethyl Bromide

HCID 21283745HCID 21283745, compound

Product 1

HCID 21283796HCID 21283796, compound

Procedure

starting from 3-(o-chlorophenyl)-5-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole and ethyl bromide there is obtained a mixture of isomeric N-ethyltriazoles and therefrom there are obtained pure 1-ethyl-5-(o-chlorophenyl)-3-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole as a resinous product, 1H-NMR(CDCl3): 1.47 (t, CH2CH3), 4.10 (q, CH2CH3); and pure 1-ethyl-3-(o-chlorophenyl)-5-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole, likewise as a resinous product, 1H-NMR(CDCl3): 1.45 (t, CH2CH3), 4.04 (q, CH2CH3);

Workup

customthere is obtained

Sources & evidence

ORD record: ord-314ef783eb3643cb9a9a4acd7aba4131
Source dataset: uspto-grants-1988_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04788210

Reaction notes

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