Ethyl Bromide → HCID 21283752, compound

HRID 2232443Notes

Reaction equation

HRID 2232443 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:12]=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:19]([F:22])([F:21])[F:20])[NH:10][N:9]=1.[CH2:23](Br)[CH3:24]>>[CH2:23]([N:10]1[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:19]([F:22])([F:20])[F:21])=[N:12][C:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[F:1])=[N:9]1)[CH3:24]

Participants

3

Reactant 2

HCID 6332Ethyl BromideHCID 21283776HCID 21283776, compound

Product 1

HCID 21283752HCID 21283752, compound

Procedure

starting from 3-(o-fluorophenyl)-5-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole and ethyl bromide there is obtained a mixture of isomeric N-ethyltriazoles and therefrom there are obtained pure 1-ethyl-3-(o-fluorophenyl)-5-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole, m.p. 72°-74° C.; and pure 1-ethyl-5-(o-fluorophenyl)-3-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole, 1H-NMR(CDCl3): 1.51 (t, CH3), 4.23 (q, CH2), 7.05-8.1 (8 aromatic H);

Workup

  1. customthere is obtained

Sources & evidence

ORD record
ord-acdd10b1fb1c4096996ecd6293516f98
Source dataset
uspto-grants-1988_11
Patent number
US04788210

Reaction notes

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