Cyclohexyl isocyanate → HCID 20523351, compound

HRID 223273Notes

Reaction equation

HRID 223273 reaction equation
[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][CH2:5][OH:6].[CH:8]1([N:14]=[C:15]=[O:16])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1>>[CH:8]1([NH:14][C:15](=[O:16])[O:6][CH2:5][CH2:4][CH2:3][N:2]([CH3:7])[CH3:1])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 18502Cyclohexyl isocyanateHCID 766463-(Dimethylamino)-1-propanol

Product 1

HCID 20523351HCID 20523351, compound

Procedure

77.3 g of 3-dimethylamino-1-propanol are reacted with 94 g of cyclohexyl isocyanate in accordance with Example 13. Distillation of the reaction product yields 153.4 g (92.8%) of analytically pure product (analysis by gas chromatography) with a boiling point of 105° C./0.015 torr. IR spectrum: 3320 cm-1NH, 1700 cm-1C=O, no bands between 2000 and 2500 cm-1.

Workup

  1. distillationDistillation of the reaction product
  2. customyields 153.4 g (92.8%) of analytically pure product (analysis by gas chromatography) with a boiling point of 105° C./0.015 torr

Sources & evidence

ORD record
ord-da6e18ca016b446db386443344080076
Source dataset
uspto-grants-1982_10
Patent number
US04352913

Reaction notes

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