HRID2232752

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1

HCID70670

Acetic acid, (triphenylphosphoranylidene)-, ethyl ester

C22H21O2P

HCID14547229

未命名化合物

PRODUCTS

生成物

$结构：CCOC(=O)/C=C\C=C(c1cccc(OC)c1)c1cccc(OC)c1$

HCID86742565

未命名化合物

结构：CCOC(=O)/C=C/C=C(c1cccc(OC)c1)c1cccc(OC)c1

HCID86742566

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

In the manner described in Example 99, 3,3-bis(3-methoxyphenyl)-2-propenal (24.8 g) was reacted with (carbethoxymethylene)triphenylphosphorane (33 g) in ethanol (100 ml) for 30 minutes at 50° C. The mixture of esters obtained from the usual work up was purified by HPLC (hexane-ether; 9:1) to give 2.3 g of the less polar (Z)-5,5-bis(3-methoxyphenyl)-2,4-pentadienoic acid ethyl ester as an oil, and 19.8 g of (E)-5,5-bis (3-methoxyphenyl)-2,4-pentadienoic acid ethyl ester.

WORKUP

后处理

customobtained from the usual work
customup was purified by HPLC (hexane-ether; 9:1)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-593ff6fc54c94d00b553c6778f3b9325
来源数据集: uspto-grants-1988_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04788206
来源说明: uspto-grants-1988_11

反应 SMILES

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=2)=[CH:10][CH:11]=O)[CH:6]=[CH:7][CH:8]=1.[C:21]([CH:26]=P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)([O:23][CH2:24][CH3:25])=[O:22]>C(O)C>[CH2:24]([O:23][C:21](=[O:22])/[CH:26]=[CH:11]\[CH:10]=[C:9]([C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=1)[C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=1)[CH3:25].[CH2:24]([O:23][C:21](=[O:22])/[CH:26]=[CH:11]/[CH:10]=[C:9]([C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=1)[C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=1)[CH3:25]