Ethyl Bromide → 1-(4-Chloro-3-trifluoromethyl-phenyl)-4-ethyl-piperazine

HRID 2232897Notes

Reaction equation

HRID 2232897 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)=[CH:4][C:3]=1[C:14]([F:17])([F:16])[F:15].Br[CH2:19][CH3:20]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:13][CH2:12][N:11]([CH2:19][CH3:20])[CH2:10][CH2:9]2)=[CH:4][C:3]=1[C:14]([F:15])([F:17])[F:16]

Participants

3

Reactant 2

HCID 6332Ethyl BromideHCID 27781371-(4-Chloro-3-(trifluoromethyl)phenyl)piperazine

Product 1

HCID 223451911-(4-Chloro-3-trifluoromethyl-phenyl)-4-ethyl-piperazine

Procedure

Beginning with 1-(4-Chloro-3-trifluoromethyl-phenyl)-piperazine and bromo-ethane, the title compound was recovered by the procedure described in Example 2. MS m/z (rel. intensity, 70 eV) 293 (M+, 6), 292 (30), 277 (29), 57 (bp), 56 (41).

Workup

  1. customthe title compound was recovered by the procedure

Sources & evidence

ORD record
ord-d0ba7b65952a48219013cd31cd124eee
Source dataset
uspto-grants-2010_05
Patent number
USRE041315E1

Reaction notes

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