Iodoethane → 4-(4-Chloro-3-trifluoromethyl-phenyl)-1-ethyl-piperidine

HRID 2232900Notes

Reaction equation

HRID 2232900 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)=[CH:4][C:3]=1[C:14]([F:17])([F:16])[F:15].I[CH2:19][CH3:20]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][CH2:12][N:11]([CH2:19][CH3:20])[CH2:10][CH2:9]2)=[CH:4][C:3]=1[C:14]([F:17])([F:15])[F:16]

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 166793174-[4-Chloro-3-(trifluoromethyl)phenyl]piperidine

Product 1

HCID 223451894-(4-Chloro-3-trifluoromethyl-phenyl)-1-ethyl-piperidine

Procedure

Beginning with 4-(4-Chloro-3-trifluoromethyl-phenyl)-piperidine and iodoethane, the title compound was recovered by the procedure described in Example 2. MS m/z (rel. intensity, 70 eV) 291 (M+, 6), 278 (29), 277 (11), 276 (bp), 70 (50).

Workup

  1. customthe title compound was recovered by the procedure

Sources & evidence

ORD record
ord-1f811f25d45941b6a21d7a56d474b62b
Source dataset
uspto-grants-2010_05
Patent number
USRE041315E1

Reaction notes

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