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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2232928Generated: October 31, 2026

Piperazine → 1-(3-Chloro-5-(trifluoromethyl)phenyl)piperazine

https://huagongshe.com/reaction/2232928

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazineHCID 4837—
Reactant1,3-Dichloro-5-(trifluoromethyl)benzeneHCID 35361—
Product1-(3-Chloro-5-(trifluoromethyl)phenyl)piperazineHCID 2234519552.1%

Reaction Steps

Beginning with 3,5-dichlorobenzotrifluoride (500 mg, 2.32 mmol) and piperazine (1 g, 11.6 mmol), 320 mg of the title compound was recovered by the procedure described in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE041315E1
Source datasetuspto-grants-2010_05
ORD IDord-bcf1280cb0754c7fb563a0e18a80ea2f
Source noteuspto-grants-2010_05