HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopropionitrile → 2-(1,3-benzothiazol-2-yl)ethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopropionitrile | HCID 1647 | — |
| Reactant | 2-Aminothiophenol | HCID 8713 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(1,3-benzothiazol-2-yl)ethanamine | HCID 4962595 | — |
Reaction Steps
A solution of 50 mg of 3-aminopropionitrile and 596 mg of 2-aminothiophenol in EtOH (15 mL) was heated at reflux for six h. After cooling the solution to room temperature, the reaction was concentrated and the residue was purified by silica gel chromatography to afford the title compound as a red oil. MS (M+H)+=179.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709473B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-1fd12dcc2a8149c4a2a880aee1a32940 |
| Source note | uspto-grants-2010_05 |