Hydrochloric Acid → HCID 68448342, compound

Participants

Reaction Steps

1,1-Dimethylethyl 7-[({1-[(7-fluoro-3-oxo-5,6-dihydro-3H-pyrrolo[1,2,3-de]quinoxalin-6-yl)methyl]-4-piperidinyl}amino)methyl]-2,3-dihydro-1H-pyrido[3,4-b][1,4]oxazine-1-carboxylate (91 mg, 0.165 mmol) in dichloromethane (2 ml) and methanol (1.5 ml) was treated with 4M hydrogen chloride in 1,4-dioxane (3.5 ml). After standing at room temperature for 2.5 h, the mixture was evaporated. The residue was triturated twice with ether and dried to give the title compound (89 mg).

Provenance & Evidence