Aniline → 4-Carbamoyl-1-phenyl-pyridinium hydrochloride

Participants

Reaction Steps

A suspension of 30.0 g 4-Carbamoyl-1-(2,4-dinitro-phenyl)-pyridinium hydrochloride and 22.4 g aniline in 600 ml methanol was stirred at room temperature for four days. The suspension was warmed to 55° C. and stirred at this temperature for one hour. The resulting solution was cooled and the solvent removed in vacuo. The resulting residue was suspended in 300 ml propan-2-one and stirred at room temperature. The insoluble residue was filtered and dried in vacuo to obtain 27.3 g 4-Carbamoyl-1-phenyl-pyridinium hydrochloride.

Provenance & Evidence