Hydrochloric Acid → HCID 86628019, compound

Participants

Reaction Steps

To a solution of (1,1-dimethylethyl {1-[2-(2-oxo-2H-chromen-8-yl)ethyl]-4-piperidinyl}carbamate (320 mg, 0.86 mmol) in 20% MeOH/CH2Cl2 (5 mL) at 0° C. was added a solution of HCl in dioxane (4 M, 1.0 mL). The reaction was warmed to RT and stirred for 16 h, then the solvents were removed under reduced pressure to afford the title compound (170 mg, 73%) as a pale yellow solid: MS (ES) m/e 273.0 (M+H)+.

Provenance & Evidence