Ammonia → HCID 59296042, compound

HRID 2233383Notes

Reaction equation

HRID 2233383 reaction equation
Cl[S:2]([C:5]1[CH:14]=[C:13]2[C:8]([C:9]([C:16]([OH:18])=[O:17])=[CH:10][NH:11][C:12]2=[O:15])=[CH:7][CH:6]=1)(=[O:4])=[O:3].Cl.[NH3:20]>>[NH2:20][S:2]([C:5]1[CH:14]=[C:13]2[C:8]([C:9]([C:16]([OH:18])=[O:17])=[CH:10][NH:11][C:12]2=[O:15])=[CH:7][CH:6]=1)(=[O:4])=[O:3]

Participants

4

Reactant 3

HCID 222AmmoniaHCID 313Hydrochloric AcidHCID 59295966HCID 59295966, compound

Product 1

HCID 59296042HCID 59296042, compound

Procedure

7-(Chlorosulfonyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid (1 g) was added to 0.880 ammonia (60 ml) and the mixture was stirred for 18 h. Concentrated hydrochloric acid was added to acidify the mixture, which was filtered to yield 7-(aminosulfonyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid as a white solid.

Workup

  1. filtrationwas filtered

Sources & evidence

ORD record
ord-b3a8e6a49ed648a1b81fade2e90c26d8
Source dataset
uspto-grants-2010_05
Patent number
US07709500B2

Reaction notes

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