HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233394Generated: October 30, 2026
HCID 59295921, compound → 2-(carboxymethyl)-4-fluorobenzoic acid
https://huagongshe.com/reaction/2233394
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 59295921 | HCID 59295921 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 2-(carboxymethyl)-4-fluorobenzoic acid | HCID 345395 | — |
Reaction Steps
A suspension of dimethyl [5-fluoro-2-(methoxycarbonyl)phenyl]malonate (1.80 g) in concentrated hydrochloric acid (25 ml) was heated at 110° C. for 48 h. The reaction was cooled and the subtitle compound collected as a white solid by filtration (1.0 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07709500B2 |
|---|
| Source dataset | uspto-grants-2010_05 |
|---|
| ORD ID | ord-2ca36af58f414a0ca311e19f37e4d677 |
|---|
| Source note | uspto-grants-2010_05 |
|---|
