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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233410Generated: October 30, 2026

2-Hydroxy-1,3-benzothiazole-6-carboxylic acid → N-{4-[4-(3,4-Dichlorophenoxy)piperidin-1-yl]-3-hydroxybutyl}-2-oxo-2,3-dihydro-1,3-benzothiazole-6-carboxamide

https://huagongshe.com/reaction/2233410

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Hydroxy-1,3-benzothiazole-6-carboxylic acidHCID 14116709—
Reactant4-Amino-1-[4-(3,4-dichlorophenoxy)piperidin-1-yl]butan-2-olHCID 59296069—
ProductN-{4-[4-(3,4-Dichlorophenoxy)piperidin-1-yl]-3-hydroxybutyl}-2-oxo-2,3-dihydro-1,3-benzothiazole-6-carboxamideHCID 59296029—

Reaction Steps

Prepared as described in Example 1 from 4-amino-1-[4-(3,4-dichlorophenoxy)piperidin-1-yl]butan-2-ol (0.26 g) and 2-oxo-2,3-dihydro-1,3-benzothiazole-6-carboxylic acid (0.152 g). Title compound obtained as a white solid (0.105 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709500B2
Source datasetuspto-grants-2010_05
ORD IDord-2941c281dff94c80ba2e04bf303c1990
Source noteuspto-grants-2010_05