HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzeneacetonitrile, 2-fluoro- → α-[(2-Fluorophenyl)methyl]-3-pyridinemethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzeneacetonitrile, 2-fluoro- | HCID 67592 | — |
| Reactant | Ethyl Nicotinate | HCID 69188 | — |
| Product | α-[(2-Fluorophenyl)methyl]-3-pyridinemethanamine | HCID 22299528 | — |
| Product | HCID 60797714 | HCID 60797714 | — |
Reaction Steps
The title compound was generated from commercially available nicotinic acid ethyl ester and (2-fluoro-phenyl)-acetonitrile according to the general procedure D described above. The intermediates 2-(2-fluoro-phenyl)-1-pyridin-3-yl-ethanone and 2-(2-fluoro-phenyl)-1-pyridin-3-yl-ethylamine were isolated and characterized.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709507B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-4e676fcbd6684caaaadff071dec477f8 |
| Source note | uspto-grants-2010_05 |