Hydrazine hydrate (1:1) → HCID 13233889, compound
Reaction equation
[CH3:1][C:2]1[N:3]([C:7]2[CH:12]=[CH:11][C:10]([C:13](=O)[CH2:14][CH2:15][C:16]([OH:18])=O)=[CH:9][CH:8]=2)[CH:4]=[CH:5][N:6]=1.O.[NH2:21][NH2:22]>>[CH3:1][C:2]1[N:3]([C:7]2[CH:12]=[CH:11][C:10]([C:13]3[CH2:14][CH2:15][C:16](=[O:18])[NH:21][N:22]=3)=[CH:9][CH:8]=2)[CH:4]=[CH:5][N:6]=1Participants
3
Procedure
Similarly, reaction of 4-(2-methyl-1H-imidazol-1-yl)-γ-oxobenzenebutanoic acid with hydrazine hydrate according to the procedure of this Example gives 4,5-dihydro-6-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone.
Sources & evidence
- ORD record
- ord-f45e345879c44847ba580f6caca49f94
- Source dataset
- uspto-grants-1982_10
- Patent number
- US04353905
Reaction notes
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