Hydrazine hydrate (1:1) → HCID 20146330, compound

HRID 223346Notes

Reaction equation

HRID 223346 reaction equation
[C:1]1([C:7]2[N:8]([C:12]3[CH:17]=[CH:16][C:15]([C:18](=O)[CH2:19][CH2:20][C:21](O)=[O:22])=[CH:14][CH:13]=3)[CH:9]=[CH:10][N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.O.[NH2:26][NH2:27]>>[C:1]1([C:7]2[N:8]([C:12]3[CH:17]=[CH:16][C:15]([C:18]4[CH2:19][CH2:20][C:21](=[O:22])[NH:26][N:27]=4)=[CH:14][CH:13]=3)[CH:9]=[CH:10][N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20146337HCID 20146337, compound

Product 1

HCID 20146330HCID 20146330, compound

Procedure

Similarly, reaction of 4-(2-phenyl-1H-imidazol-1-yl)-γ-oxobenzenebutanoic acid with hydrazine hydrate according to the procedure of this Example gives 4,5-dihydro-6-[4-(2-phenyl-1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone.

Sources & evidence

ORD record
ord-5c42bee24d674cccb1e01d84b2030c3c
Source dataset
uspto-grants-1982_10
Patent number
US04353905

Reaction notes

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