HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorzoxazone → HCID 131728101, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorzoxazone | HCID 2733 | — |
| Reactant | Hexyl isocyanate | HCID 75659 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 131728101 | HCID 131728101 | — |
Reaction Steps
100 mg (0.59 mmol) of 5-chloro-3H-benzooxazol-2-one were reacted in analogy to Example 1 with 112.6 mg (0.885 mmol) of 1-isocyanatohexane in the presence of ethyldiisopropylamine in THF at 70° C. Yield: 125 mg (71%), M+H+: 297.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709513B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-e405f35c22774b2981de06c8e7155165 |
| Source note | uspto-grants-2010_05 |