Sodium Hydroxide → HCID 136399784, compound

HRID 2233538Notes

Reaction equation

HRID 2233538 reaction equation
C(OC1C(OC(=O)C)C(OC(=O)C)C(COC(=O)C)OC1[C:24]1[C:32]2[C:28](=[N:29][C:30](=[O:33])[N:31]=2)[CH:27]=[CH:26][C:25]=1[C:34]([O-])=O)(=O)C.[OH-:37].[Na+]>C(O)C>[OH:37][C:26]1[C:25]([CH3:34])=[CH:24][C:32]2=[N:31][C:30](=[O:33])[N:29]=[C:28]2[CH:27]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 131728104HCID 131728104, compound

Product 1

HCID 136399784HCID 136399784, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution of (16) (0.30 g, 1.32 mmol) in 10% sodium hydroxide (5 ml) and ethanol (5 ml) was heated under reflux for 1.5 h. When cooled to room temperature the ethanol was removed in vacuo and the mixture was filtered to give (18) as a white solid (0.20 g, 92%).

Workup

  1. temperatureunder reflux for 1.5 h
  2. customwas removed in vacuo
  3. filtrationthe mixture was filtered

Sources & evidence

ORD record
ord-d803c5a68ce14826894f0ad760e7ac3f
Source dataset
uspto-grants-2010_05
Patent number
US07709514B2

Reaction notes

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