反应详情

90 g (0.6 mole) of salicylic acid hydrazide and 388.8 g (2.4 moles) of triethyl orthoacetate in 500 ml of n-propanol are refluxed for 84 hours. When the mixture has cooled, the precipitate is filtered off and recrystallized from a mixture of toluene and petroleum ether. 47 g of colorless crystals (26.7% of theory) are obtained; melting point 74°-76° C.

1. temperatureWhen the mixture has cooled
2. filtrationthe precipitate is filtered off
3. customrecrystallized from a mixture of toluene and petroleum ether