참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-(4-Chlorophenoxy)acetone | HCID 239874 | — |
| 반응물 | (2-Bromo-5-nitrophenyl)hydrazine | HCID 53402499 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | HCID 68617744 | HCID 68617744 | — |
반응 단계
A mixture of the compound from (i) (2.4 g) and 1-(4-Chloro-phenoxy)-propan-2-one (1.65 g) in MeCN (20 ml) and water (5 ml) was stirred for 16 h. The volatiles were removed in vacuo. AcOH (50 ml) was added and the reaction heated at 75° C. for 72 h. The volatiles were evaporated under reduced pressure and the residue was purified by chromatography on silica eluting with 5% ethylacetate/iso-hexane. Yield 0.34 g
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07709521B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_05 |
|---|
| ORD ID | ord-bd892b9f6f3440b48b6590ad1fbadcc5 |
|---|
| 출처 메모 | uspto-grants-2010_05 |
|---|
