Potassium Carbonate → HCID 86609235, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of the product from step (i) (0.60 g), potassium carbonate (0.516 g) and methyl bromoacetate (0.26 ml) in DMF (4 ml) was stirred at 50° C. for 4 h. The reaction was partitioned between ethylacetate/water. The organics were washed with water, dried and evaporated under reduced pressure. The residue was purified by chromatography on silica eluting with 10-20% ethylacetate/iso-hexane. Yield 0.44 g

Provenance & Evidence