Ethanesulfonyl chloride → HCID 11604213, compound

HRID 2233753Notes

Reaction equation

HRID 2233753 reaction equation
[CH2:1]([S:3](Cl)(=[O:5])=[O:4])[CH3:2].[NH2:7][C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[N:13]([CH2:17][C:18]([O:20]C)=[O:19])[C:12]([CH3:22])=[C:11]2[O:23][C:24]1[CH:29]=[CH:28][C:27]([Cl:30])=[CH:26][CH:25]=1>>[Cl:30][C:27]1[CH:28]=[CH:29][C:24]([O:23][C:11]2[C:10]3[C:14](=[CH:15][CH:16]=[C:8]([NH:7][S:3]([CH2:1][CH3:2])(=[O:5])=[O:4])[CH:9]=3)[N:13]([CH2:17][C:18]([OH:20])=[O:19])[C:12]=2[CH3:22])=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 11667Ethanesulfonyl chlorideHCID 866092365-Amino-3-(4-chlorophenoxy)-2-methyl-1H-indole-1-acetic acid, methyl ester

Product 1

HCID 11604213HCID 11604213, compound

Procedure

The title compound was prepared by the method of example 7 step (iii) using ethanesulfonyl chloride and the product from example 7 step (ii). Yield 155 mg

Sources & evidence

ORD record
ord-7eac16e351874bd6b91bc4f7ddfbc973
Source dataset
uspto-grants-2010_05
Patent number
US07709521B2

Reaction notes

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