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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233824Generated: November 1, 2026

2,2-Dimethyl-1,3-dioxane-4,6-dione → Ethyl 4-(1,3-dioxoisoindolin-2-YL)-3-oxobutanoate

https://huagongshe.com/reaction/2233824

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 16249—
Reactant2H-Isoindole-2-acetyl chloride, 1,3-dihydro-1,3-dioxo-HCID 81242—
ProductEthyl 4-(1,3-dioxoisoindolin-2-YL)-3-oxobutanoateHCID 701239—

Reaction Steps

The title compound was prepared in a manner analogous to Intermediate 123 starting from 2,2-dimethyl-1,3-dioxane-4,6-dione and (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709503B2
Source datasetuspto-grants-2010_05
ORD IDord-c9ba32ba12514cc9b946a480ccc69925
Source noteuspto-grants-2010_05