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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233851Generated: November 1, 2026

HCID 86608250, compound → HCID 86608251, compound

https://huagongshe.com/reaction/2233851

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86608250HCID 86608250—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 86608251HCID 86608251—

Reaction Steps

Tert-butyl 1-[6-chloro-4-(1,2,4-oxadiazol-3-yl)pyridin-2-yl]piperidin-4-ylcarbamate (Intermediate 55) (50 mg 0.13 mmol) was dissolved in 4 N HCl in dioxane (2 ml). The mixture was stirred at room temperature for 2 h. The solvent was concentrated in vacuo to afford the crude title compound which was used without further purification. (74 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709503B2
Source datasetuspto-grants-2010_05
ORD IDord-b4b07c71bbcc45a088430a815defeeb0
Source noteuspto-grants-2010_05