HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86608250, compound → HCID 86608251, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86608250 | HCID 86608250 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86608251 | HCID 86608251 | — |
Reaction Steps
Tert-butyl 1-[6-chloro-4-(1,2,4-oxadiazol-3-yl)pyridin-2-yl]piperidin-4-ylcarbamate (Intermediate 55) (50 mg 0.13 mmol) was dissolved in 4 N HCl in dioxane (2 ml). The mixture was stirred at room temperature for 2 h. The solvent was concentrated in vacuo to afford the crude title compound which was used without further purification. (74 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709503B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-b4b07c71bbcc45a088430a815defeeb0 |
| Source note | uspto-grants-2010_05 |