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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233899Generated: October 30, 2026

Methyl4-chloroquinoline-2-carboxylate → HCID 46941938, compound

https://huagongshe.com/reaction/2233899

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl4-chloroquinoline-2-carboxylateHCID 19066063—
ReactantMethyl 2-{4-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-1,3-thiazole-5-carboxylateHCID 59679281—
ProductHCID 46941938HCID 46941938—

Reaction Steps

The title compound was prepared by a procedure analogous to Intermediate 133 starting with methyl 4-chloroquinoline-2-carboxylate (WO 9505378). The product was purified on a silica gel flash column (0→5% MeOH in DCM) followed by recrystallization from EtOAc.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709503B2
Source datasetuspto-grants-2010_05
ORD IDord-1e42c11e93734919bb675e6375a4ae1f
Source noteuspto-grants-2010_05