N-(3-Aminopropyl)morpholine → HCID 86608265, compound

HRID 2233904Notes

Reaction equation

HRID 2233904 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:16]=[C:17]([Cl:19])[N:18]=1)[C:5]([NH:7][CH2:8][CH2:9][N:10]1[CH2:15][CH2:14]OCC1)=[O:6].[N:20]1([CH2:26]CCN)[CH2:25][CH2:24][O:23][CH2:22][CH2:21]1.ClC1C=C(C=C(Cl)N=1)C(O)=[O:35]>>[Cl:19][C:17]1[CH:16]=[C:4]([CH:3]=[C:2]([Cl:1])[N:18]=1)[C:5]([NH:7][C:8](=[O:35])[C@@H:9]1[CH:26]([N:20]2[CH2:25][CH2:24][O:23][CH2:22][CH2:21]2)[CH2:14][CH2:15][NH:10]1)=[O:6]

Participants

4

Reactant 3

HCID 61055N-(3-Aminopropyl)morpholineHCID 948302,6-Dichloroisonicotinic acidHCID 432358692,6-Dichloro-N-[2-(4-morpholinyl)ethyl]-4-pyridinecarboxamide

Product 1

HCID 86608265HCID 86608265, compound

Procedure

The title compound was prepared by the procedure of Intermediate 40 from 3-morpholin-4-yl-propan-1-amine and 2,6-dichloroisonicotinic acid (both commercially available).

Sources & evidence

ORD record
ord-6a2b24effce84ab78c53daa417f6e53a
Source dataset
uspto-grants-2010_05
Patent number
US07709503B2

Reaction notes

Loading…