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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233920Generated: October 25, 2026

3,5-dimethyl-1H-pyrrole-2-carboxylic acid → 2-Chloro-6-(4-{[(3,5-dimethyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)isonicotinamide

https://huagongshe.com/reaction/2233920

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-dimethyl-1H-pyrrole-2-carboxylic acidHCID 2776468—
ReactantHCID 86608255HCID 86608255—
Product2-Chloro-6-(4-{[(3,5-dimethyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)isonicotinamideHCID 86608273—

Reaction Steps

Title compound was synthesized by an analogous method to Example 18 using 2-(4-aminopiperidin-1-yl)-6-chloroisonicotinamide hydrochloride (Intermediate 70) and 3,5-dimethyl-1H-pyrrole-2-carboxylic acid (commercially available).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709503B2
Source datasetuspto-grants-2010_05
ORD IDord-5e4d7ca0f8db48bc9e85b4a17bb695a4
Source noteuspto-grants-2010_05