3-ethyl-4,5-dimethyl-1H-pyrrole-2-carboxylic Acid → 2-Chloro-6-(4-{[(3-ethyl-4,5-dimethyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)isonicotinamide

Participants

Role	Name	HCID	Charge
Reactant	3-ethyl-4,5-dimethyl-1H-pyrrole-2-carboxylic Acid	HCID 10329685	—
Reactant	2-(4-Aminopiperidin-1-yl)-6-chloroisonicotinamide hydrochloride	HCID 86608255	—
Product	2-Chloro-6-(4-{[(3-ethyl-4,5-dimethyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)isonicotinamide	HCID 86608274	—

Reaction Steps

Title compound was synthesized by an analogous method to Example 18 by coupling 2-(4-aminopiperidin-1-yl)-6-chloroisonicotinamide hydrochloride (Intermediate 70) with 3-ethyl-4,5-dimethyl-1H-pyrrole-2-carboxylic acid (commercially available).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07709503B2
Source dataset	uspto-grants-2010_05
ORD ID	ord-908005d20ada479abbba319168b680fa
Source note	uspto-grants-2010_05