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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233923Generated: October 30, 2026

3,4-diethyl-5-methyl-1H-pyrrole-2-carboxylic acid → 2-Chloro-6-(4-{[(3,4-diethyl-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)isonicotinamide

https://huagongshe.com/reaction/2233923

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-diethyl-5-methyl-1H-pyrrole-2-carboxylic acidHCID 15899541—
Reactant2-(4-Aminopiperidin-1-yl)-6-chloroisonicotinamide hydrochlorideHCID 86608255—
Product2-Chloro-6-(4-{[(3,4-diethyl-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)isonicotinamideHCID 86608275—

Reaction Steps

Title compound was synthesized by an analogous method to Example 18 by coupling 2-(4-aminopiperidin-1-yl)-6-chloroisonicotinamide hydrochloride (Intermediate 70) with 3,4-diethyl-5-methyl-1H-pyrrole-2-carboxylic acid (commercially available).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709503B2
Source datasetuspto-grants-2010_05
ORD IDord-d15439374ab44551bd9ee179d2088691
Source noteuspto-grants-2010_05