HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichloro-5-ethyl-1H-pyrrole-2-carboxylic acid → 2-(4-{[(3,4-Dichloro-5-ethyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)-1,3-thiazole-5-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichloro-5-ethyl-1H-pyrrole-2-carboxylic acid | HCID 68579708 | — |
| Reactant | HCID 68579945 | HCID 68579945 | — |
| Product | 2-(4-{[(3,4-Dichloro-5-ethyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)-1,3-thiazole-5-carboxamide | HCID 68582574 | — |
Reaction Steps
Title compound was synthesized by an analogous method to Example 29 by coupling 3,4-dichloro-5-ethyl-1H-pyrrole-2-carboxylic acid (Intermediate 73) with 2-(4-aminopiperidin-1-yl)-1,3-thiazole-5-carboxamide hydrochloride (Intermediate 81).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709503B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-10881ef819ec41d98e32b9688e370ee6 |
| Source note | uspto-grants-2010_05 |