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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233963Generated: October 31, 2026

1-Methyl-2-imidazolecarboxaldehyde → 4-Bromo-5-methyl-N-{1-[(1-methyl-1H-imidazol-2-yl)methyl]piperidin-4-yl}-1H-pyrrole-2-carboxamide

https://huagongshe.com/reaction/2233963

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-2-imidazolecarboxaldehydeHCID 139575—
ReactantHCID 68579819HCID 68579819—
Product4-Bromo-5-methyl-N-{1-[(1-methyl-1H-imidazol-2-yl)methyl]piperidin-4-yl}-1H-pyrrole-2-carboxamideHCID 68580014—

Reaction Steps

Title compound was synthesized by an analogous method to Example 1 by coupling 4-bromo-5-methyl-N-piperidin-4-yl-1H-pyrrole-2-carboxamide hydrochloride (Intermediate 57) with 1-methyl-1H-imidazole-2-carbaldehyde (commercially available).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709503B2
Source datasetuspto-grants-2010_05
ORD IDord-c892e9141c0d4caab548f81fbffee484
Source noteuspto-grants-2010_05