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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233966Generated: October 30, 2026

2-Bromo-1,3-benzothiazole → N-[1-(1,3-benzothiazol-2-yl)piperidin-4-yl]-4-bromo-5-methyl-1H-pyrrole-2-carboxamide

https://huagongshe.com/reaction/2233966

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1,3-benzothiazoleHCID 612040—
ReactantHCID 68579819HCID 68579819—
ProductN-[1-(1,3-benzothiazol-2-yl)piperidin-4-yl]-4-bromo-5-methyl-1H-pyrrole-2-carboxamideHCID 68582949—

Reaction Steps

Title compound was synthesized by an analogous method to Example 123 by coupling 4-bromo-5-methyl-N-piperidin-4-yl-1H-pyrrole-2-carboxamide hydrochloride (Intermediate 57) with 2-bromo-1,3-benzothiazole (commercially available).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709503B2
Source datasetuspto-grants-2010_05
ORD IDord-43bab24f15dd4a498704f29a7c10edaa
Source noteuspto-grants-2010_05