HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(trifluoromethyl)-1H-indole-2-carboxylic Acid → HCID 68582822, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(trifluoromethyl)-1H-indole-2-carboxylic Acid | HCID 4563246 | — |
| Reactant | tert-Butyl 4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidine-1-carboxylate | HCID 68579743 | — |
| Reactant | HCID 68579819 | HCID 68579819 | — |
| Product | HCID 68582822 | HCID 68582822 | — |
Reaction Steps
Title compound was synthesized by an analogous method to Intermediate 2 by coupling 4-bromo-5-methyl-N-piperidin-4-yl-1H-pyrrole-2-carboxamide hydrochloride (Intermediate 57) with 4-(trifluoromethyl)-1H-indole-2-carboxylic acid (J. Am. Chem. Soc. 1957, 79, 1745).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709503B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-7330eb1ebc0747d0aa1783c8097a6d5c |
| Source note | uspto-grants-2010_05 |