O-Methylhydroxylamine hydrochloride → HCID 86608330, compound

HRID 2233984Notes

Reaction equation

HRID 2233984 reaction equation
[Cl:1][C:2]1[C:6]([Cl:7])=[C:5]([CH3:8])[NH:4][C:3]=1[C:9]([NH:11][CH:12]1[CH2:17][CH2:16][N:15]([C:18]2[N:23]=[C:22]([C:24](O)=[O:25])[CH:21]=[C:20]([O:27][CH3:28])[N:19]=2)[CH2:14][CH2:13]1)=[O:10].Cl.[O:30]([NH2:32])[CH3:31]>>[Cl:1][C:2]1[C:6]([Cl:7])=[C:5]([CH3:8])[NH:4][C:3]=1[C:9]([NH:11][CH:12]1[CH2:17][CH2:16][N:15]([C:18]2[N:23]=[C:22]([C:24]([NH:32][O:30][CH3:31])=[O:25])[CH:21]=[C:20]([O:27][CH3:28])[N:19]=2)[CH2:14][CH2:13]1)=[O:10]

Participants

3

Reactant 2

HCID 521874O-Methylhydroxylamine hydrochlorideHCID 68580053HCID 68580053, compound

Product 1

HCID 86608330HCID 86608330, compound

Procedure

The title compound was synthesized by an analogous method to Example 8 starting from 2-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)-6-methoxypyrimidine-4-carboxylic acid (Example 174) and methoxylamine hydrochloride.

Sources & evidence

ORD record
ord-82f531d8e0714fe3a75f3b868ffaceaf
Source dataset
uspto-grants-2010_05
Patent number
US07709503B2

Reaction notes

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