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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233993Generated: October 26, 2026

HCID 68579996, compound → Methyl 2-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)-6-(ethylthio)pyrimidine-4-carboxylate

https://huagongshe.com/reaction/2233993

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68579996HCID 68579996—
ReactantMethyl 2-chloro-6-(ethylthio)pyrimidine-4-carboxylateHCID 86038397—
ProductMethyl 2-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)-6-(ethylthio)pyrimidine-4-carboxylateHCID 68579937—

Reaction Steps

The title compound was synthesized by a method analogous to Example 9 by coupling methyl 2-chloro-6-(ethylthio)pyrimidine-4-carboxylate (Intermediate 96) with 3,4-dichloro-5-methyl-N-piperidin-4-yl-1H-pyrrole-2-carboxamide hydrochloride (Intermediate 1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709503B2
Source datasetuspto-grants-2010_05
ORD IDord-e126055884cc4e4aa79b2bb65be05da6
Source noteuspto-grants-2010_05