O-Methylhydroxylamine hydrochloride → HCID 86608342, compound

HRID 2234037Notes

Reaction equation

HRID 2234037 reaction equation
[Cl:1][C:2]1[C:6]([Cl:7])=[C:5]([CH3:8])[NH:4][C:3]=1[C:9]([NH:11][CH:12]1[CH2:17][CH2:16][N:15]([C:18]2[CH:23]=[CH:22][N:21]=[C:20]([C:24](O)=[O:25])[CH:19]=2)[CH2:14][CH2:13]1)=[O:10].Cl.[O:28]([NH2:30])[CH3:29]>>[Cl:1][C:2]1[C:6]([Cl:7])=[C:5]([CH3:8])[NH:4][C:3]=1[C:9]([NH:11][CH:12]1[CH2:17][CH2:16][N:15]([C:18]2[CH:23]=[CH:22][N:21]=[C:20]([C:24]([NH:30][O:28][CH3:29])=[O:25])[CH:19]=2)[CH2:14][CH2:13]1)=[O:10]

Participants

3

Reactant 2

HCID 521874O-Methylhydroxylamine hydrochlorideHCID 68580270HCID 68580270, compound

Product 1

HCID 86608342HCID 86608342, compound

Procedure

The title compound was synthesized by an analogous method to Example 8 starting from 4-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)pyridine-2-carboxylic acid (Example 293) and methoxylamine hydrochloride.

Sources & evidence

ORD record
ord-2512fae86b3e49ee9dbba57f1bf3f763
Source dataset
uspto-grants-2010_05
Patent number
US07709503B2

Reaction notes

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