O-Methylhydroxylamine hydrochloride → HCID 86608344, compound

HRID 2234050Notes

Reaction equation

HRID 2234050 reaction equation
[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][O:11][C:12]1[N:17]=[C:16]([C:18]([OH:20])=O)[CH:15]=[C:14]([N:21]2[CH2:26][CH2:25][CH:24]([NH:27][C:28]([C:30]3[NH:31][C:32]([CH3:37])=[C:33]([Cl:36])[C:34]=3[Cl:35])=[O:29])[CH2:23][CH2:22]2)[N:13]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl.[O:39]([NH2:41])[CH3:40]>>[Cl:35][C:34]1[C:33]([Cl:36])=[C:32]([CH3:37])[NH:31][C:30]=1[C:28]([NH:27][CH:24]1[CH2:23][CH2:22][N:21]([C:14]2[CH:15]=[C:16]([C:18]([NH:41][O:39][CH3:40])=[O:20])[N:17]=[C:12]([O:11][CH2:10][CH2:9][NH:8][C:6](=[O:7])[O:5][C:1]([CH3:3])([CH3:4])[CH3:2])[N:13]=2)[CH2:26][CH2:25]1)=[O:29]

Participants

3

Reactant 2

HCID 521874O-Methylhydroxylamine hydrochlorideHCID 68579891HCID 68579891, compound

Product 1

HCID 86608344HCID 86608344, compound

Procedure

The title compound was synthesized by an analogous method to Example 8 starting from 2-{2-[(tert-butoxycarbonyl)amino]ethoxy}-6-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)pyrimidine-4-carboxylic acid (Example 154) and methoxylamine hydrochloride.

Sources & evidence

ORD record
ord-baca1a2a738c418586e9955d99a92088
Source dataset
uspto-grants-2010_05
Patent number
US07709503B2

Reaction notes

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