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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2234078Generated: October 31, 2026

2-(3-methoxy-6-pyridin-4-yl-pyridazin-4-yl)-3-vinyl-1H-indole methanol → 3-Ethyl-2-(3-methoxy-6-pyridin-4-yl-pyridazin-4-yl)-1H-indole

https://huagongshe.com/reaction/2234078

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-methoxy-6-pyridin-4-yl-pyridazin-4-yl)-3-vinyl-1H-indole methanolHCID 86612050—
CatalystPalladiumHCID 23938—
Product3-Ethyl-2-(3-methoxy-6-pyridin-4-yl-pyridazin-4-yl)-1H-indoleHCID 23092455—

Reaction Steps

12 mg Palladium, 10% on charcole are added to a solution of 70 mg 2-(3-methoxy-6-pyridin-4-yl-pyridazin-4-yl)-3-vinyl-1H-indole methanol and the reaction mixture stirred under an hydrogen atmosphere for 4 hours. The catalyst is removed by filtration and the solvens by evaporation yielding the product which was used without further purification

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709466B2
Source datasetuspto-grants-2010_05
ORD IDord-e563169108b34dc588c7ee27e0ed70cc
Source noteuspto-grants-2010_05