反应详情

10 g of 3-oxo-6-pyridin-4-yl-2,3-dihydro-pyridazine-4-carboxylic acid ethyl ester are dissolved in 150 ml of ethanol, 4.2 ml of hydrazine hydrate is added and the mixture is refluxed for 5 hours. After cooling to room temperature, the solid is collected by filtration and dried in vacuo at 40° C.

1. temperaturethe mixture is refluxed for 5 hours
2. filtrationthe solid is collected by filtration
3. customdried in vacuo at 40° C.