HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → HCID 135961905, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | HCID 135961844 | HCID 135961844 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | HCID 135961905 | HCID 135961905 | — |
Reaction Steps
39 mg of 4-(1H-indol-2-yl)-6-(1H-pyrazol-4-yl)-2H-pyridazin-3-one is dissolved in dimethoxyethane and 28 mg of N-bromosuccinimide is added. The solution is stirred for 3 h at RT. The product is purified by preparative RP-HPLC eluting with a gradient of 0-100% acetonitrile in water (+0.01% trifluoroacetic acid). Yield 11 mg. LC-MS (ES+) 355/357 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709466B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-404f4f3664c2416bb8163748d1a92c6c |
| Source note | uspto-grants-2010_05 |