反应详情

3-[2-(4-Bromophenyl)ethoxy]-N-(2,2-diethoxyethyl)-N-phenethyl-propanamide (Example 10c) 0.72 g) was dissolved in anhydrous dioxane (15 mL) and treated with concentrated hydrochloric acid (10 mL) and stirred for 1 hour. The reaction mixture was then poured into dichloromethane (15 mL), washed with water (2×30 mL) and brine (30 mL). The organic layer was separated, dried over anhydrous magnesium sulphate, filtered and concentrated to give the sub-titled compound (0.54 g) as a viscous oil.

1. washwashed with water (2×30 mL) and brine (30 mL)
2. customThe organic layer was separated
3. dry with materialdried over anhydrous magnesium sulphate
4. filtrationfiltered
5. concentrationconcentrated